Specification :

Supplied by GNI
Gentcare Natural Ingredients, Inc.
Add: Room 1106, # 13-3 Chang Fang Dong Jun,
# 111 East RenMin Anvenue, Changsha,
Hunan, 410016, China
Phone: + 86-731-8228 7663
Fax: + 86-731-8228 4663
Mobile phone: + 86 139 0748 7460
E-mail: naturalextract@ vip.163.com
MSN: lisirhn@ hotmail.com
Alitalk ID: Rogerleigh
Trademanager ID: Rogerleigh
www.GNI-Natural.com www.gentcare.com

Product Name: Mangosteen Extract, Alpha-mangotin, Mangosteen Polyphenols
Latin Name: Garcinia mangostana L.
Plant part used: Fruit Rind ( Pericarp)
Active Ingredient: Alpha-mangostin, Mangosteen Polyphenols, Garma-mangosteen
Specification: Detailed
Test Method: HPLC & .UV
Cas No.: 6147-11-1
Main Function: Antioxidants

Brief Introduction
Synonyms---Xango, Mangostan, Queen of fruits
Alpha-Mangostin
Chemical Name 1, 3, 6-trihydroxy-7-methoxy-2, 8-bis£ ¨ 3-methylbut-2-enyl£ © xanthen-9-one
Molecu lar Formula C24H26O6
Molecular Weight £ ¨ g/ mol£ © 410.45964
Molecular Structure:

Chemical structures of mangostins
Alpha-mangostin : R1 = CH3, R2 = R3 = H
Beta-mangostin : R1 = R3 = CH3, R2 = H
Gamma-mangostin : R1 = R2 = R3 = H

Mangosteen ( Garcinia mangostana Linn.) is a tropical evergreen fruit tree of the family Guttiferae, with deep reddish purple fruit, cultivated in Southeast Asian countries. In Thailand, the fruit of this plant is very popular and has been known as the ¡ ° Queen of fruits¡ ± . Despite the name, this tree is not related to the mango. The fruit rind of this plant has been used in Thai traditional medicine for treatment of diarrhea and skin infections. For hundreds of years, the people of Southeast Asia have used mangosteen, especially the rind, to ward off and treat infections, reduce pain or control fever, and treat various other ailments. In countries where the tree grows, native healers use various parts of the plant. Its fruit, including the rind and pulp, can be pureed together and sold as a drink. Its rind may be dried and powdered, and substances are also extracted from its bark. The juice or puree is eaten or drunk. In Asia and the Philippines, the rind may be steeped in water to make tea. Some folk healers prepare an ointment or salve to apply to the skin for conditions such as eczema, injuries, and infections. Others boil the leaves and bark of the tree to make a medicinal drink or to mix with other herbs to apply to wounds. The roots may be boiled to make a drink for women with menstrual problems.

Mangosteen rind contains tannins ( polyphenols) and xanthones i.e. alpha-, beta- and gamma-mangostins. Alpha-mangostin is a major component, which possess anti-inflammatory and antibacterial activities against methicillin-resistant Staphylococcus aureus, S. epidermidis, and Propionibacterium acne , which is the critical eticologic agent in acne. It was also reported to inhibit alveolar duct formation in a mouse mammary organ culture model and to suppress the carcinogen induced formation of aberrant crypt foci in a short-term colon carcinogenesis model. In Thailand, mangosteen fruit extract is popularly used as a food supplement while the fruit rind extract has been used in herbal cosmetics and pharmaceutical products.

Benefits
Anti-oxidant
Anti-aging
Anti-cancer
Anti-bacterial
Suppo rt microbiological balance
Help the immune system
Improve joint flexibility
Provide mental support
Treat diarrhea
Treat infections
Treat tuberculosis

Mechanism
Mangosteen is touted for its antioxidants, especially xanthones ( a type of chemical in certain plants) . Independent scientific research studies showed that Mangosteen contains more than 40 xanthones ( Alpha-mangostin is a major component) , - roughly 20% of about 200 xanthones found in nature. The Mangosteen is the single, most abundant source of xanthones known to science. A number of these xanthones were demonstrated in scientific studies to be even more potent antioxidant than vitamins C and E, two of the most powerful antioxidants found in food. They were also shown in scientific and pharmacological studies to possess a variety of immune-system-boosting and healing properties, such as supporting microbiological balance, helping the immune system, improving joint flexibility, and providing mental support. Some proponents claim that it can help diarrhea, infections, tuberculosis, cancer, and a host of other illnesses.

Safety
Are there any possible problems or complications? No ill effects have been reported to date. Alpha-mangostin and common Mangosteen Rind or Fruit Extract are safe. But relying on this type of treatment alone, and avoiding conventional medical care, may have serious health consequences.

Dosage
" The typical dose is 300-900mg ( 90% alpha-mangostin) per day ( usually in 2-3 doses throughout the day) .
" Consult physicians for different condition specifics.
GNI¡ ¯ s Alpha-mangostin Features and Benefits:
Manosteen Extract is one of GNI' s most competitive products, with many advantages as list in the following, produced as our patent-pending process and know-how technology from Garcinia mangostana Linn. rind.
" Produced with pure water only
" High purity: over 95%
" NO solvent - residual free
" Pesticide-free
" Crystal Bright Light Yellow in appearance
" High anti-bacteria, and longer shelf life

Product Specifications:
5% -95% ¦ � -Mangostin EU. HPLC,
0.3% -8% ¦ Ã -Mangostin HPLC,
5% -95% Xanthones EU. HPLC,
30% Polyphenol( Tannins) UV Folin-C from dry fruit pericarp ( Brown color) ,
10% Alpha-mangostin EU. HPLC with 30% Polyphenols from dry fruit pericarp ( Red Brown) ,
5% Alpha-mangostin EU. HPLC with 15% Polyphenols from from fresh fruit ( Red Color) .
Juice Powder 10: 1( about 20% Polyphenols) , 20: 1( about 30% Polyphenols)

They are all very good powder extracts, strictly standardized, of natural red-biege color ( from fresh fruit) or brown to bright light yellow color ( from dry fruit pericarp) , preserving the natural fine scent and taste of the plant. The extracts from fresh fruit have ideal water solubility and with the least sediments and almost no suspended substance in their solvents, which are suitable for drink use. The extracts from dry fruit pericarp is of high contents of alpha-, beta-, garma-mangostin, the active ingredients, which are for pharmaceuticals or health products use.