Specification :

Product name: raltegravir and its intermediates
Intermediate 1: 2-( 2-aminopropan-2-yl) -N-( 4-fluorobenzyl) -5-hydroxy-1-ethyl-6-oxo-1, 6-dihy dropyrimidine-4-carboxamide ( CAS No.: 518048-03-8)
Intermediate 2: benzyl 2-( 4-( 4-fluorobenzylcarbamoyl) -5-hydroxy-1-methyl-6-oxo-1, 6-dihydro pyrimidin-2-yl) propan-2-yl) propan-2-yl carbamate ( CAS No.: 518048-02-7)
Intermediate 3: Methyl 2-( 2-( benzyloxycarbonylamino) propan-2-yl) -5-hydroxy-1-methyl-6-oxo-1, 6-dihyd ropyrimidine-4-carboxylate ( CAS No.: 888504-27-6)
Intermediate 4: Methyl 2-( 2-( benzyloxycarbonylamino) propan-2-yl) -5, 6-dihydroxypyrimidine-4-carboxyl ate ( CAS No.: 519032-08-7)
Intermediate 5: potassium 5-methyl-1, 3, 4-oxadiazole-2-carboxylate ( CAS No.: 888504-28-7)
Intermediate 6: 5-methyl-[ 1, 3, 4] -oxadiazole-2-carboxylic acid ( CAS No.: 518048-06-1)
Impurity: Total impurity: no more than 1.0%
Any impurity: no more than 0.5%
Water content: no more than 1.0%
Assay: no less than 98%
Indication: An antiretroviral drug, used to treat HIV infection