Specification :

Prulifloxacin CAS Number: 123447-62-1
Chemical Name: Prulifloxacin
Synonyms: 1H, 4H-[ 1, 3] Thiazeto[ 3, 2-a] quinoline-3-carboxylic acid, 6-fluoro-1-methyl-7-[ 4-[ ( 5-methyl- 2-oxo-1, 3-dioxol-4-yl) methyl] -1- piperazinyl] -4-oxo-; PUFX; Prulifloxacin ( JAN) ; ( + -) -7-( 4-( ( Z) -2, 3-Dihydroxy-2-butenyl) -1-piperazinyl) -6-fluoro-1-meth yl-4-oxo-1H, 4H-( 1, 3) thiazeto( 3, 2-a) quinoline-3-carboxylic acid, cyclic carbonate; 1H, 4H-( 1, 3) Thiazeto( 3, 2-a) quinoline-3-carboxylic acid, 6-fluoro-1-methyl-7-( 4-( ( 5-methyl-2-oxo-1, 3-dioxol-4-yl) methyl) -1-piperaziny l) -4-oxo-; Sword; Prulifloxacin [ INN] ; Sword ( TN) ; Prulifloacin
Molecular Formula: C21H20FN3O6S
Molecular Weight: 461.46
Appearance: light yellow to off white crystalline powder
Density: 1.62 g/ cm3
Boiling Point: 633.2 ° C at 760 mmHg
Flash Point: 336.8 ° C
Solubility: Slightly soluble in dimethyl formamide, 0.1M NaOH or glacial acetic acid; insoluble in water or methanol
It’ s intermediate:
Ethyl 6, 7-difluoro-2-ethylmercapto-4-hydroxy quinoline-3-carboxylate;
Ethyl 4-acetoxy-6, 7-difluoro-2-ethylmercaptoquinoline-3-carboxylate;
Ethyl 6, 7-difluoro-1-methyl-4-oxo-4H-[ 1, 3] thiazeto[ 3, 2-a] quinoline-3-carboxylate;
Ethyl 6-fluoro-1-methyl-4-oxo-7-( 1-piprazinyl) -4H-[ 1, 3] thiazeto[ 3, 2-a] quinoline-3- carboxylate;
6-Fluoro-1-methyl-4-oxo-7-( 1-piperazinyl) -4H-[ 1, 3] thiazeto[ 3, 2- a] quinoline-3-carboxylic acid