AG-1478

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M.Wt: 352.22
Formula: C16H14ClN3O2.HCl
Solubility: Soluble to 5 mM in DMSO
Purity: > 99 %
Storage: Desiccate at -20° C
CAS 153436-53-4, 170449-18-0

Potent and selective inhibitor of epidermal growth factor receptor kinase ( IC50 values 3 nM for EGFR and > 100 ¼ M for ErbB2 and PDGFR) . Inhibits proliferation of NCI-H2170 NSCLC cells in vitro ( IC50 = 1 ¼ M) .

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