CUDC-101

Quantity Order:

Payment Method:

Cashier Order, Bank Cheque

M.Wt: 434.49
Formula: C24H26N4O4
Solubility: Unknown
Purity: > 99%
Storage: -20 2 years
CAS 1012054-59-9

CUDC-101 is a drug which displays potent in vitro inhibitory activity against HDAC, EGFR, and HER2 with an IC50 of 4.4, 2.4, and 15.7 nM, respectively. [ 1] This drug has novel structure incorporating HDAC inhibitory functionality into the pharmacophore of the EGFR and HER2 inhibitors. [ 1] In most tumor cell lines tested, CUDC-101 exhibits efficient antiproliferative activity with greater potency than vorinostat ( SAHA) , erlotinib, lapatinib, and combinations of vorinostat/ erlotinib and vorinostat/ lapatinib. [ 2] In vivo, CUDC-101 promotes tumor regression or inhibition in various cancer xenograft models including nonsmall cell lung cancer ( NSCLC) , liver, breast, head and neck, colon, and pancreatic cancers. [ 2]

Recommended Products

GDC0941

GDC0449

GDC0879

Gefitinib

Abiraterone( CB-7598)

ABT-26 3

ABT-737

ABT-888

AZD1152-HQPA

BEZ-235

BIBF1120

PTC-124

SGX-523

BIBW 2992

Bortezomib

CP-690550

Elvitegravir

FTY720

LBH-589

LY2140023( LY4040 39)

LY294002

NVP-AUY922

NVP-TAE684

PD-0325901

PD-153035 hydrochloride

PF-04217903

Vandetanib

Vatalanib, Dihydrochloride Salt

VX-680 ( MK-0457) ( Tozasertib)

ZSTK-474

BIX02188

AZD2281

A-769662

Rivaroxaban

R esveratrol

Prasugrel

Eltrombopag

LY450139

AZ-23

VX-950( Telaprevir)

Cal citriol

Calcifediol; monohydrate

R-406

CUDC-101

CP-724714

AG-1478 hydrochloride

AS-1413( Amonafide)

1H-Benzimidazole, 1-[ 4-chloro-6-( 4-morphol inyl) -1, 3, 5-triazin-2-yl] -2-( difluoromethyl) -

A-966492

Contact: orders@ bioc hempartner.com

Recommend to your friends