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Sunitinib malate
Quantity Order:
Wt: 532.56
Formula: * * * * * 4H2O5
Solubility: Soluble to 25 mM in DMSO
Purity: > 99 %
Storage: Store at + 4° C
CAS No: [ 341031-54-7]
Potent, ATP-competitive VEGFR, PDGFR² and KIT inhibitor ( Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFR² and KIT respectively) . Also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models
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