Specification :

Camptothecin
Chemical Name:
4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3, 14(4H,12H)-dione
Molecular Formula: C20H16N2O4
Molecular Weight: 348.36
CAS No.: 7689-03-4
Melting Point : 260¡æ
Solubility:Hardly dissolve in water,slightly dissolve in DMSO
Appearance: Light yellow crystalline powder
Pharmacology Action: Camptothecin (CPT) is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I (topo I). It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. It was isolated from the bark and stem of Camptotheca acuminata (Camptotheca, Happy tree), a tree native in China