Dandruff free by Ciclopirox Olamine

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Origin:

China

Ciclopirox Olamine

INCI Name : Ciclopirox Olamine
Chemical Name / Synonyms : Ciclopirox ethanolamine; 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2( 1H) -one 2-aminoethanol ( 1: 1)
CAS No. : 41621-49-2; 29342-05-0 ( free form)
EINECS : 255-464-9
Molecular Formula : C12H17NO2.C2H7NO; C14H24N2O3

Function
Cosmetic Biocide
Ciclopirox has broad-spectrum action against dermatophytes, yeast, and fungi. Its anti-inflammatory activity has been demonstrated in human polymorphonuclear cells. This agent also inhibits prostaglandin and leukotriene synthesis. Ciclopirox olamine was effective and safe for mild-to-moderate dandruff.

Use Level
Recommendatory amount of usage: 1-1.5%

SPECIFICATIONS ( USP 30) :
Description White crystalline powder
Ciclopirox content 97.5-101.5%
Ethanolamine content 223-230mg/ g
Residue on ignition Not more than 0.1%
Loss on drying Not more than 1.5%
pH 8.0-9.0
Heavy metals Not more than 10ppm
Related Substances Impurity A

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