Rhodiola L. is widely distributed in Arctic and mountainous regions throughout Europe and Asia. It grows at altitudes of 1500 to 4000 metres above sea level. The herb had been used in traditional folk medicine in China, Mongolia Siberia, and the Carpathian Mountains of the Ukraine. It has been used to decrease fatigue and increase the body’s natural resistance to various stresses. It also used for the treatment of tuberculosis cancer and sexual disturbances. Now the Extracts of this plant produce favorable changes in a variety of diverse areas of physiological function, including neurotransmitter levels, central nervous system activity, and cardiovascular function.