Cissus Quadrangularis

Price:

USD 1000 / Ton

Quantity Order:

Origin:

India

Payment Method:

Telegraphic Transfer (T/T), L/C

Quantity:

5 X 20' FCL 60 tons

Pack. & Delivery:

Bale of 90 kgs

Latin name: Cissus quadrangula Linn
Synonym: Vitis quadrangularis Wall
Family: Vitaceae

Cissus quadrangularis is an indigenous medicinal plant of India. The use of this plant by the common folk for promoting fracture healing process is an old practice. It has been prescribed in ancient Ayurvedic texts by Bhava Prakash and Chakra Dutta as a general tonic especially for the fractured patient. Since then it has been in extensive use by bone setters both for external application and as an internal medicine to be taken with milk. The stem of Cissus quadrangularis is also reputed in Ayurveda as alterative, anthelmintic, dyspeptic, digestive, tonic, analgesic in eye and ear diseases, in the treatment of irregular menstruation and asthma, and in complaints of the back and spine. Scientific studies have revealed the Cissus extract to possess cardiotonic and androgenic property.

Cissus quadrangularis contains high amount of vitamin C, carotene A, anabolic steroidal substances and calcium. These anabolic steroidal principles from Cissus quadrangularis showed a marked influence in the rate of fracture- healing by influencing early regeneration of all connective tissues of mesenchyma origin, namely the fibroblasts, the chondroblasts and osteoblasts involved in the healing and quicker mineralization of the callus. It has greater impact on osteoblastic proliferation than other cellular responses.

Cissus quadrangularis causes less amount of tissue reaction in the fractured region leading to optimum decalcification in the early stage with minimum of callus formation. Hence deposition of calcium is just enough to join the two broken segments of bone so that it s remodeling takes much faster. This early completion of calcification process and earlier remodeling phenomenon lead to early recovery of Cissus treated animals. Cissus is also shown to cause early gain in the tensile strength of fractured bones of about 90 per cent of its normal strength at the end of 6 week. Cissus quadrangularis builds up the chemical composition of the fractured bone namely its mucopolysaccharides, collagen, calcium, phosphorus and others as well as its functional efficiency. Mucopolysaccharides play an important role in the healing by supplying raw materials for repairs. Therefore it seems that in the early period of bone fracture healing the greater the accumulation of these materials more rapid will be the rate of healing. Rapid the utilization of these raw materials earlier will be completion of healing process. Cissus quadrangualris not only causes the greater accumulation of mucopolysaccharides but also an earlier disappearance of mucopolysaccharides from the fractured area, associated with the earlier calcification and firmer callus formation.

In clinical trials Cissus quadrangularis as per radiological and clinical observations has been found to cause considerable reduction in the healing time of fractures by 55-33 percent. In few of the treated cases, although radiologically only, an early callus formation was observed but clinically the symptoms of fracture such as pain, tenderness, and swelling were significantly absent.

Cissus quadrangularis is shown to neutralize the anti-anabolic effect of steroids like cortisone in healing of fractures. Antianabolic effects of cortisone include inhibition of tissue regeneration and repair, also retarding formation of the specific skeletal structures. In such conditions even if the cartilage tissue is produced, its maturation and ultimate bone replacement do not take place in the normal pattern. It has main inhibitory action on fibroblasts and mast cells, which produce mucopolysaccharides of connective tissue. There have been reports that continuous intake of corticosteroids induces osteoporosis and pseudofractures in the bone.

Imbalance in the activities of osteoclasts ( cells responsible for bone loss) and osteoblasts ( cells responsible for bone formation) may lead to osteoporosis and fractures in postmenopausal women. In osteoporosis, the bones begin to deteriorate due to calcium deficiency as a result of the body' s efficiency in maintaining mineral balance in the blood at the expense of bone integrity. During menopause the decrease in hormones affects the body' s ability to maintain calcium levels resulting in an increased loss of minerals from the bones. Postmenopausal women are at particular risk to osteoporosis because the loss of estrogen associated with the menopause leads to bone loss of much greater magnitude than one would expect on the basis of age alone. Cissus quadrangularis with significant ability to inhibit antianabolic effects and bone fracture healing effects is likely to exert some beneficial effects on recovery of bone mineral density in postmenopausal osteoporosis.
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Pl find below our company' s profile, there you can find our herbs and herbal products list. Pl do contact us for your requirement.

We Packiam Botanicals have been dedicated to dealing and wholesale exporting of Medicinal herbs as well as related products like Herbal juices, leaves t-cut and powders and extracts for more than 19 years. With factories in India, we are able to offer a wide range of herbs all at competitive prices and guaranteed on-time delivery.

Our herbs have gained a great popularity at Japan, European, American, Taiwan, Philippines, China, Ghana markets. We hope to have the opportunity to count with your cooperation to expand our activity into your market. We are confident that the professionalism and dedication of Packiam Botanicals will guarantee the best quality and supply to our buyers.

Our dealings extend through many herbs like Gymnema leaves and powder, Senna leaves, Pods and stems, Morinda Tinctoria fruit, Aloe Vera leaves dried, Ocimum Sanctum ( Tulsi) leaves, Sapindus Mukurossi ( Soapnut) , Henna leaves and Powder, Amla, Papaya leaves, Neem leaves and pods, Phyllanthus Niruri, Lemon grass cut, Tribullus Terristris, Stevia leaves, Passiflora herbs, Hydrocotyle Asiatica ( Gotukola) , Ashwagantha root, Calamus root, Garcinia cambogia, Gloriosa superba seeds, Liquorice root, Cyprus Rotandus, Mint leaves, Moringa oleifera leaves and seeds ( Drumstick) , Andrographis Paniculata, Yellow dock root, Asparagus racemosus, Momordica Charantia, Tamarind fruit, etc., and Herbal Products like Gymnema leaves t-cut, Senna leaves t-cut, Morinda ( NONI) Juice with Stevia as sweetener, Soapnut shells in 500 gms and 1kg pack, Stevia products like STEVIA WHITE POWDER, STEVIA GREEN LEAF POWDER, Stevia extract powder, Herbal Tea, Herbal Massage oil, hair oil, and Herbal Extracts.

Should you have any question, please do not hesitate to contact us. We will be very pleased to provide any information you may require.

We believe it will be a good opportunity for both of us to further expanding our business relations.

Thanks for your kind attention. We look forward to hearing from you soon.

Please visit us at: http: / / packiam.8m.com/ for full product list.

Await your favorable reply.

With kind regards / M.Balasubramanian

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