Specification :

Fenvalerate

Common name: fenvalerate
IUPAC name: ( RS) -a-cyano-3-phenoxybenzyl ( RS) -2-( 4-chlorophenyl) -3-methylbutyrate
Chemical Abstracts name: cyano( 3-phenoxyphenyl) methyl 4-chloro-a-( 1-methylethyl) benzeneacetate
CAS RN: [ 51630-58-1] unstated stereochemistry

PHYSICAL CHEMISTRY
Composition: Tech. grade fenvalerate is 92% pure. Mol. wt.: 419.9; M.f.: C25H22ClNO3; Form: Tech. fenvalerate is a viscous yellow or brown liquid, sometimes partly crystalline at room temperature. M.p.: 39.5-53.7 ° C ( pure) . B.p.: Decomposes on distillation. V.p.: 1.92x10-2 mPa ( 20 º C) . KOW: logP = 5.01 ( 23 º C) . S.g./ density: 1.175 ( 25 º C) . Solubility: In water 5000 mg/ kg. Slightly irritating to skin and eyes ( rabbits) .
Inhalation: LC50 for rats > 101 mg/ m3.
NOEL: ( 2 y) for rats 250 mg/ kg diet.
ADI: 0.02 mg/ kg b.w.
Toxicity class: WHO ( a.i.) II; EPA ( formulation) II

ECOTOXICOLOGY
Birds: Acute oral LD50 for domestic fowl > 1600, mallard ducks 9932 mg/ kg. Dietary LC50 for quail > 10 000, mallard ducks 5500 mg/ kg.
Fish: LC50 ( 96 h) for rainbow trout 0.0036 mg/ l.
Bees: Toxic to bees. Contact LD50 0.23 ug/ bee.

ENVIRONMENTAL FATE
Animals: In mammals, following oral administration, fenvalerate is rapidly metabolised. Up to 96% is excreted in the faeces within 6-14 days. For a study of the metabolism of fenvalerate in the laying hen.
Plants: In plants, fenvalerate is split into two parts by cleavage of the ether group, followed by further hydroxylation in the 2- and 4- positions of the phenoxy ring, and hydrolysis of the nitrile group to amide and carboxyl groups. The majority of the acids and phenols thus formed are converted into glucosides.
Soil/ Environment: In aqueous media, the ester bond is hydrolysed. In light, decarboxylation occurs, with recombination of the cleaved moieties. DT50 in soil c. 75-80 d.