Ingredient and purity : 15% min Petasins ( petasin + isopetasin). C20H28O3. CAS:[26577-85-5].PA free. This extract powder have not S-petasin Function : Petasin is responsible for the antispasmodic properties of the plant by reducing spasms in smooth muscle and vascular walls, in addition to providing an anti-inflammatory effect by inhibiting leukotriene synthetics. Petasin has also been found to be treat migraine headache, asthma , bronchitis. Butterbur has also been used for cough ; urination and stomach problems.