Products Catalog

Specification

SNP genotyping for medium to ultra-high throughput analysis

The GenomeLab SNPstream Genotyping System provides an automated scalable system capable of performing from 4,600 to over 3,000,000 SNP genotypes per day. Combined with multiplexing capabilities, experimental layouts and operational flexibility, this enables you to process a wide range of studies.

Product Features
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GenomeLab SNPstream is an automated multiplexed system that can process either 12 or 48 SNPs in each well of an arrayed 384-well plate.

12-plex or 48-plex SNP Genotyping

* The GenomeLab SNPstream is an automated multiplexed system that can process either 12 or 48 SNPs in each well of an arrayed 384-well plate. This system operates at a consistent cost per sample, regardless of run throughput, allowing users to cost-effectively zero in on research targets with low throughput studies as well as conduct high-throughput analyses.
* T-2050A: Rapid, Robust and Cost-Effective SNP Analysis with the 48-Plex GenomeLab SNPstream Genotyping System (PDF Format)

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Hardware

* In a bench-top design, the GenomeLab SNPstream Genotyping System utilizes single-base primer extension technology in a tagged fluorescent assay to deliver an automated, scalable solution for your medium to ultra-high throughput analysis. It comes with reagents, software and instrumentation developed to work optimally together, as well as a two-color CCD-based imager.

Integrated Software--Fully Automated Workflow From Raw Data to Genotype Summary Report

* The SNPstream software suite is a comprehensive set of advanced, easy-to-use tools that work together to provide a seamless workflow, from primer design to 384-well setup, analysis of image data, and genotype calls. Large amounts of data in batch format are handled with minimal user interaction for increased data integrity and ultra-high throughput processing.
* Seamless Workflow--Up to 72 Plates Unattended

SNPware® Reagent Kits

SNPware® Reagent Kits

SNPware Reagent Kits (12- or 48-plex)

* Our preformulated, ready-to-use SNPware® Reagent Kits are optimized for effortless and robust single-base primer extension reactions. The kits include ready-to-use reagents for simple addition reactions, all performed in the original PCR* plate. No precipitation or filtration steps are required.

SNPware Tag Array Plate

SNPware Tag Array Plate

Tag Array Method

* Multiplexed reactions are spatially resolved on a SNPware Tag Array plate. Each of the 384 wells in a plate contain 16 or 52 unique oligonucleotides of a known sequence, or tag. Each tag on the plate is complementary to one of the tags of the 12 or 48 extension primers, plus four controls to ensure accuracy. After transfer to the Tag Array plate, each SNP hybridizes to its complementary tag. SNPs are then identified by their position in the well.

(Related with Biomek series)

for more information please visit : (http://www.beckmancoulter.com/products/instrument/geneticanalysis/ceq/genom elab_snpstream_dcr.asp)