Specification :

CAS: 25122-46-7
MF: C25H32ClFO5
MW: 466.97
EINECS: 246-634-3
Product Categories: Organics; Intermediates & Fine Chemicals; Pharmaceuticals
Mol File: 25122-46-7.mol
mp 195.5-1970C
Hazard Codes Xi
Risk Statements 36/ 37/ 38
Safety Statements 26-36
Chemical Properties White Crystalline Powder
Usage Topical corticosteroid. Glucocorticoid; anti-inflammatory
Clobetasol propionate ( phonetic pronunciation: kloh-BAY-tuh-sall) is a corticosteroid used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/ oak. Clobetasol belongs to US Class I ( Europe: class IV) of the corticosteroids, making it one of the most potent available. It comes in shampoo, mousse, ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use ( beyond two weeks) . It is also used to treat several auto-immune diseases including alopecia areata, vitiligo and lichen planus ( auto immune skin nodules) .
Clobetasol propionate is marketed and sold worldwide under numerous names including Clobex, Cosvate ( India) , Temovate ( US) , Olux, Tenovate, Dermovate, Dermatovate, Butavate, Movate, Novate.
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