Welcome to
biochempartner
Free Member
biochempartner
China
Home
Company Info
Contact Us
Trade Offers
[40]
Selling Offers
[40]
Products Catalog
[1]
PKI587
Share your thoughts
Write a review
Recommend to your friends
Language
English
Sell
See larger image
AZD1152-hqpa
Quantity Order:
Payment Method:
Bank Cheque
M.Wt: 507.56
Formula: C26H30FN7O3
Solubility: DMSO
Purity: > 99%
Storage: at -20 2 years
CAS No.: 722544-51-6
AZD1152 is a dihydrogen phosphate prodrug of a pyrazoloquinazoline Aurora kinase inhibitor [ AZD1152– hydroxyquinazoline pyrazol anilide ( HQPA) ] and is converted rapidly to the active AZD1152-HQPA in plasma . AZD1152-HQPA is a highly potent and selective inhibitor of Aurora B ( Ki, 0.36 nM) compared with Aurora A ( Ki, 1, 369 nM) and has a high specificity versus a panel of 50 other kinases. Consistent with inhibition of Aurora B kinase, addition of AZD1152-HQPA to tumor cells in vitro induces chromosome misalignment, prevents cell division, and consequently reduces cell viability and induces apoptosis.
www.biochempartner.com
Recommend to your friends
showing 38 of 41
Prev : NVP-BEZ 235
Next : AZD1152
You have [
3
] new inquiries
.
Go to Member Menu
Home
-
Trade List
-
Product List
-
Inquiry List
-
Cooperation List
-
Company List
Copyright © 2024
Indotrade.co
. All Rights Reserved.