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    PAROXETINE Impurities & Metabolites

    PAROXETINE Impurities & Metabolites

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    PRX01: Paroxetine [ CAS # 61869-08-7]

    PRX02: Paroxetine HCl [ CAS # 78246-49-8]

    PRX03: Paroxetine HCl Hemihydrate [ CAS # 110429-35-1]

    PRX04: Paroxetine Formate

    PRX05: Paroxetine Acetate

    PRX06: Paroxetine Sulfate

    PRX07: Paroxetine Phosphate

    PRX08: Paroxetine Maleate

    PRX09: Paroxetine USP Related Compound A; Paroxetine EP Impurity B;

    CAS Name: ( 3S, 4R) -trans-4-( p-Methoxyphenyl) -3-[ ( 3, 4-methylenedioxy) phenoxy] methylpiper idine hydrochloride ( " 4-Methoxy Paroxetine Hydrochloride " )

    PRX10: Paroxetine EP Impurity A; Anhydrous Paroxetine EP Impurity A

    CAS Name: ( 3S, 4R) -trans-4-Phenyl-3-[ ( 3, 4-methylenedioxy) phenoxy] methylpiperidine ( " Desfluoro Paroxetine " )

    PRX11: Paroxetine USP Related Compound B ( Acetate)

    CAS Name: ( 3S, 4R) -trans-4-Phenyl-3-[ ( 3, 4-methylenedioxy) phenoxy] methylpiperidine acetate ( " Desfluoro Paroxetine Acetate " )

    PRX12: Paroxetine EP Impurity C

    CAS Name: ( 3S, 4R) -trans-4-( p-Ethoxyphenyl) -3-[ ( 3, 4-methylenedioxy) phenoxy] methylpiperi dine hydrochloride ( " 4-Ethoxy Paroxetine Hydrochloride " )

    PRX13: Paroxetine USP Related Compound C; Paroxetine EP Impurity D; Anhydrous Paroxetine EP Impurity D; trans-( + ) -Paroxetine Hydrochloride

    CAS Name: ( 3R, 4S) -trans-( + ) -4-( p-Fluorophenyl) -3-[ ( 3, 4-methylenedioxy) phenoxy] methylpi peridine hydrochloride

    PRX14: Paroxetine USP Related Compound D; Paroxetine EP Impurity E; Anhydrous Paroxetine EP Impurity E; cis-Paroxetine Hydrochloride

    CAS Name: ( 3R, 4R) -trans-4-( p-Fluorophenyl) -3-[ ( 3, 4-methylenedioxy) phenoxy] methylpiperi dine hydrochloride

    PRX15: Paroxetine USP Related Compound E; Paroxetine EP Impurity G; Anhydrous Paroxetine EP Impurity G

    CAS Name: 4-( 4-Fluorophenyl) -1-methyl-1, 2, 3, 6-tetrahydro pyridine

    PRX16: Paroxetine USP Related Compound F; N-Methyl Paroxetine ( " NMP" )

    CAS Name: ( 3S, 4R) -trans-( -) -1-Methyl-3-[ 1, 3-benzodioxol-5-yloxy) methyl] -4-( fluoropheny l) piperidine [ CAS # 110429-36-2]

    PRX17: ( 3R, 4S) -N-Methyl Paroxetine

    CAS Name: ( 3R, 4S) -trans-( + ) -1-Methyl-3-[ 1, 3-benzodioxol-5-yloxy) methyl] -4-( fluoropheny l) piperidine

    PRX18: ( ± ) -3-Ethoxycarbonyl-4-( 4-fluoro phenyl) -1-methylpiperidin-2, 6-dione ( unresolved)

    PRX19: ( ± ) -4-( 4-Fluorophenyl) -3-hydroxymethyl-1-methylpiperidine ( unresolved)

    PRX20: ( 3S, 4R) -trans-( -) -4-( 4-Fluorophenyl) -3-hydroxymethyl-1-methylpiperidine
    [ CAS # 105812-81-5]

    PRX21: ( 3R, 4S) -trans-( + ) -4-( 4-Fluorophenyl) -3-hydroxymethyl-1-methylpiperidine

    PRX 22: ( 3R, 4R) -cis-( + ) -4-( 4-Fluorophenyl) -3-hydroxymethyl-1-methylpiperidine

    PRX23 : ( 3S, 4S) -cis-( -) -4-( 4-Fluorophenyl) -3-hydroxymethyl-1-methylpiperidine
    [ CAS # 153779-91-0]

    PRX24: Anhydrous Paroxetine EP Impurity I

    CAS Name: ( 3S, 4R) -trans-( -) -4-( 4-Fluorophenyl) -3-hydroxymethyl-piperidine
    [ CAS # 125224-43-3 ]

    PRX25: ( 3R, 4R) -N-Methyl Paroxetine

    CAS Name: ( 3R, 4R) -cis ( ± ) -1-Methyl-3-[ 1, 3-benzodioxol-5-yloxy) methyl] -4-( fluorophenyl) piperidine

    PRX26: Paroxetine EP Impurity F; Paroxetine Dimer

    CAS Name: Bis { 3, 4-methylenedioxy-6-[ ( 3S, 4R) -4-( 4-fluorophenyl) piperidine-3 -ylmethoxy] phenyl} methane

    PRX27: Paroxetine Dimer N-Methyl Impurity

    CAS Name: Bis { 3, 4-methylenedioxy-6-[ 1-methyl-( 3S, 4R) -4-( 4-fluorophenyl) piperidine-3 -ylmethoxy] phenyl} methane

    PRX28: Paroxetine 4-Hydroxy Metabolite; 4-HM Paroxetine;

    CAS Name: ( 3S, 4R) -4-( 4-Fluorophenyl) -3-( 4-hydroxy-3-methoxyphenoxymethyl) piperidine
    [ CAS # 112058-90-9 ]

    PRX29: Paroxetine 3-Hydroxy Metabolite; 3-HM Paroxetine;

    CAS Name: ( 3S, 4R) -4-( 4-Fluorophenyl) -3-( 3-hydroxy-4-methoxyphenoxymethyl) piperidine
    [ CAS # 112058-89-6 ]

    PRX30: Anhydrous Paroxetine EP Impurity B

    CAS Name: 1, 3-Benzodioxol-5-ol ( " Sesamol " )

    PRX31: Anhydrous Paroxetine EP Impurity C

    CAS Name: ( 3S, 4R) -3-[ ( 1, 3-Benzodioxol-5-yloxy) methyl] -1-benzyl-4-( 4-fluorophenyl) piper idine
    ( " N-Benzyl Paroxetine" )

    PRX32: Anhydrous Paroxetine EP Impurity F

    CAS Name: ( 3S, 4R) -3-[ ( 1, 3-Benzodioxol-5-yloxy) methyl] -1-benzyl-4-phenylpiperidine
    ( " N- Benzyl Desfluoro Paroxetine" )

    PRX33: Anhydrous Paroxetine EP Impurity H

    CAS Name: [ ( 3S, 4R) -1-Benzyl-4-( 4-fluorophenyl) -piperidin-3-yl] methanol
    ( " N-Benzyl Paroxol" )

    PRX34: Anhydrous Paroxetine EP Impurity J

    CAS Name: ( 3S, 4R) -3-[ ( 1, 3-Benzodioxol-5-yloxy) methyl] -4-( 4' - fluorobiphenyl-3-yl) piperidine



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