Specification :

RSP01: Risperidone

3-[ 2-[ 4-( 6-Fluoro-1, 2-benzisoxazol-3-yl) piperidin-1-yl] ethyl] -2 -methyl-6, 7, 8, 9-tetrahydro-4H-pyrido[ 1, 2-a] pyrimidin-4-one
[ CAS # 106266-06-2]

RSP02: Risperidone Chloro Impurity

3-( 2-Chloroethyl) -2-methyl-6, 7, 8, 9-tetrahydro-4H-pyrido-( 1, 2-a) -py rimidin-4-one
[ CAS # 63234-80-0]

RSP03: Risperidone Amine Impurity

6-Fluoro-3-( 4-piperidinyl) -1, 2-benzisoxazole ( free base)
[ CAS # 84163-77-9]

RSP03HCl: Risperidone Amine Impurity Hydrochloride

6-Fluoro-3-( 4-piperidinyl) -1, 2-benzisoxazole hydrochloride
[ CAS # 84163-13-3]

RSP04HCl: Risperidone Benzoyl Impurity Hydrochloride

4-( 2, 4-Difluorobenzoyl) -piperidine hydrochloride
[ CAS # 106266-04-0]

RSP05: Risperidone EP Impurity A

3-[ 2-[ 4-[ ( E) -( 2, 4-difluorophenyl) ( hydroxyimino) methyl] piperidin-1-yl] ethy l] -2-methyl-6, 7, 8, 9-tetrahydro-4H-pyrido[ 1, 2-a] pyrimidin-4-one

RSP06: Risperidone EP Impurity B

3-[ 2-[ 4-[ ( Z) -( 2, 4-difluorophenyl) ( hydroxyimino) methyl] piperidin-1-yl] ethy l] -2-methyl-6, 7, 8, 9-tetrahydro-4H-pyrido[ 1, 2-a] pyrimidin-4-one

RSP07: Risperidone EP Impurity C

( 9RS) -3-[ 2-[ 4-( 6-fluoro-1, 2-benzisoxazol-3-yl) piperidin-1-yl] ethyl] -9-hyd roxy-2-methyl-6, 7, 8, 9-tetrahydro-4H-pyrido[ 1, 2-a] pyrimidin-4-one ( " 9-Hydroxy Risperidone" )

RSP08: Risperidone EP Impurity D

3-[ 2-[ 4-( 5-fluoro-1, 2-benzisoxazol-3-yl) piperidin-1-yl] ethyl] -2-methyl-6, 7, 8, 9-tetrahydro-4H-pyrido[ 1, 2-a] pyrimidin-4-one ( " Risperidone 5-Fluoro Isomer" )

RSP09: Risperidone EP Impurity E

( 6RS) -3-[ 2-[ 4-( 6-fluoro-1, 2-benzisoxazol-3-yl) piperidin-1-yl] ethyl] -2, 6-d imethyl-6, 7, 8, 9-tetrahydro-4H-pyrido[ 1, 2-a] pyrimidin-4-one ( " 6-Methyl Risperidone" )

RSP10: Risperidone EP Impurity F

2-[ 2-methyl-4-oxo-6, 7, 8, 9-tetrahydro-4H-pyrido[ 1, 2-a] pyrimidin-3-yl] ethyl 4-( 6-fluoro-1, 2-benzisoxazol-3-yl) piperidin-1-carboxylate

RSP12: Risperidone EP Impurity H

3-[ 2-[ 4-( 2, 4-difluorobenzoyl) piperidin-1-yl] ethyl] -2-methyl-6, 7, 8, 9-tetra hydro-4H-pyrido[ 1, 2-a] pyrimidin-4-one

RSP13: Risperidone EP Impurity I

3-[ 2-[ 4-[ 4-fluoro-2-[ 4-( 6-fluoro-1, 2-benzisoxazol-3-yl) piperidin-1-yl] ben zoyl] piperidin-1-yl] ethyl] -2-methyl-6, 7, 8, 9-tetrahydro-4H-pyrido[ 1, 2-a] pyrim idin-4-one