Specification :

Leuprorelin Acetate
CAS NO 53714-56-0
purity : 98% min

1 Appearance White powder Conforms
2 Solubility Souble in water or 1% acetic acid at a concentration ofe1mg/ ml to give a clear, colorless solution Conforms
3 Identity Monoisotopic Mass: 1209.43± 1.0 1209.8
4 Specific optical rotation -38.0^ -42.0° [ ± ] 20D( c= 1, 1% HAc) -40.0°
5 Amino acid Composition Ser: present Glu: 0.85^ 1.1 Pro: 0.85^ 1.1 Leu: 0.85^ 1.1 Tyr: 0.85^ 1.1 His: 0.85^ 1.1 Arg: 0.85^ 1.1 Trp: present 0.88 0.91 1.01 2.06 1.00 0.98 0.95 present
6 Peptide Purity( By HPLC) e98.0% by area integration 99.3%
7 RelatedSubstance( BYHPLC) Total Impurities( % ) d2.0% Largest Single Impurity( % ) d0.5% 0.7% 0.4%
8 Acetate Content 4.7% ~ 9.0% 8.8%
9 Water Content( Karl Fischer) d5.0% 2.0%
10 Bacterial Endotoxins d16.7IU/ mg Conforms
11 Peptide Content e80.0% 90.2%
12 Assay( By Anhydrous, Acetic Acid-free) 97.0^ 103.0% 100.5%